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3rd Generation IgE Allergy Test - FABER
The first generation of allergy test involves binding allergenic extracts to a solid phase and then incubating this with the patient’s serum, This RAST test involves dangerous radioactive materials and could only be performed in specially equipped laboratories.
The second generation tests involve measuring the degree of colour change or the strength of the fluorescence to determine the quantity of bound anti-IgE antibodies.
Recent developments in allergy blood tests include the use of molecular allergens. Since a crude allergen extract contains many different proteins, only a few of which can cause an allergic reaction, binding to the irrelevant proteins often result in false positive results, the accuracy of the tests would improve. Another recent development is the multiplex assay, the amount of allergens needed is also greatly reduced, thus lowering the cost of the test. It also allows more allergens to be tested with a given amount of blood sample.
Faber Allergy Test employs nanotechnology and is a 3rd generation multiplex assay. It can accurately measure total IgE level up to 45,000 IU/ml in blood serum.
Why do Eczema patient are more fitted for Faber allergy testing.
One of the cause for eczema, especially young children, is Food allergies. The allergen molecules in the food bind to the IgE antibodies in the body. This triggers the release of histamine from the mast cells, which leads to an allergic reaction.
Taking peanuts for example, peanuts have 17 different allergen molecules. Among which allergen molecules with a greater chance of causing severe allergic reactions include: Ara h 2 and Ara h 6. Other molecule such as Ara h 8 has a low risk triggering an allergic reaction. Therefore, allergen molecular test is very helpful for risk assessment of allergic reactions in patients with eczema.
Eczema patients are more suitable for blood tests because the pre-existing eczema skin condition might affect and reduce the accuracy of a skin prick test.
In allergy blood tests, the 3rd generation IgE allergy test Faber has been researched for over 15 years and had eliminated those non-sensitizing proteins to reduce false positive possibilities.
In fact, there are more than 600 of allergen molecules cause allergic reactions, of which more than 300 are mold and limited to certain countries and regions. The 3rd generation IgE allergy test Faber can detect more than 200 clinically identified allergens, and is ideal for eczema patients.
In addition, the total IgE amount in patients with the more severe eczema often exceeds 1000 IU / ml. Older allergy tests often cause false positive reactions due to high IgE totals. In contrast, the latest 3rd generation allergy test Faber can test up to 45,000 IU/ml of total IgE, and the test results are more accurate.
The allergy test performed are for screening purpose only. Customers are advised to consult a doctor for any diagnosis and treatment, in which the cost is not included in the amount paid to MedDx and its appointment laboratory.